An academic paper published by a major university contains some methodologies that fit perfectly with my start up idea. I would like to incorporate the methodologies into my start up but I am concerned about the following things:
To answer you questions:
With all that in mind, it is probably worth consulting an IP attorney if you are really planning to incorporate these methodologies into your startup.
The only way to protect a methodology that is presented in a public paper is to patent it. If the university has a patent, then it could prevent you from using the methodology. Otherwise, you don't have any obligations.